Detailed information about selected course/program
EU code
13.2 - Physics
Mobility
3 - PhD
Location
Free University of Berlin, Germany
Subject
Department of Physics
Course/Program
PhD Degree in RNA folding
Language
English
Language requirements
Participants should be fluent in both written and spoken English. Applicants from countries where English is not the language of instruction need to have obtained a score of at least 550 on the TOEFL test (or a score of at least 213 on a computer TOEFL test) or provide proof of an equivalent test or provide proof that part of their education was in English. Or equal knowledge of German.
Academic requirements
M.Sc. In Physics, Chemistry, biotechnology or related. Experience in Molecular Simulations.
Max available positions
2
Information
Ribonucleic acid, RNA, is a versatile biological macromolecules. The best known function of RNA is the transfer and translation of genetic information. RNA nanotechnology exploits the fact that RNA can act as a carrier by selectively binding small molecule ligands. the shape and size of the binding pockets depends on the tertiary fold of the RNA. The folding and stabilisation of RNA is strongly influenced by metal ions such as sodium and magnesium. In this project the folding of different RNA sequences wll be investigated by molecular dynamics simulations taking into account the effect of cosolute such as salt. We are particularly interested in the sal-dependent dynamics and tertiary structure of RNA forming helix-helix junctions of three- or four-way junctions or pseudoknots.
Homepage
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Duration
36 months between Jul 15 2014 and Jul 14 2017
Contact person
Dr. Petra Imhof (petra.imhof@fu-berlin.de)