Detailed information about selected course/program
EU code
13.3 - Chemistry
Mobility
3 - PhD
Location
University of Leuven, Belgium
Subject
Chemistry
Course/Program
PhD project: Introduction of structural variation in the nucleoside backbone of enzymatic cofactors
Language
English
Language requirements
Good knowledge of English.
Academic requirements
Applicants must hold a Msc in Chemistry - Molecular Design and Synthesis
Max available positions
1
Information
In this project you will validate methods that have been designed for structural variation on the nucleoside backbone of such cofactors. Interesting features of this synthesis are a late-stage Mitsunobu reaction and a general initiation to complex protection-deprotection strategies in the synthesis of natural product analogues. Moreover, this project will introduce both small-scale reaction optimizations as well as the peculiarities of scale-up. Techniques learned: organic synthesis and characterisation (NMR, MS, IR, UV, etc..). HPLC separations.
Homepage
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Duration
36 months between Jul 15 2014 and Jul 14 2017
Contact person
Prof. Wim Dehaen (wim.dehaen@chem.kuleuven.be)