Detailed information about selected course/program
EU code
13.2 - Physics
Mobility
3 - PhD
Location
Lund University, Sweden
Subject
Physic/ Fysik
Course/Program
PhD in Applied Physics
Language
English
Language requirements
TOEFL minimum score 80
Academic requirements
The work will include theoretical modeling of light propagation in tissue, and experimental work with the instrumentation. The optimal candidate should have MSc or correspondent degree, strong aptitude to experimental work and solid background in optics, physics and math. Experience in Matlab programming is advantageous as well as interest in biomedicine and application oriented projects. Work in close collaboration with other members of the group/ scientists, excellent English and very good communication skills are prerequisite for this position
Max available positions
1
Information
Systemic radiation therapy is a treatment modality where radioactive isotopes are administered to a patient. Within the research of developing new radiopharmaceuticals for cancer therapy the isotopes are fused to a targeting molecule, e.g. an antibody. In this way the radiopharmaceutical is selectively taken up in malignant tissue, rendering a localized and specific radiation dose to the tumor only. This research is performed in pre-clinical studies and there is a need to image the subjects undergoing treatment longitudinally, i.e. over time. A relatively novel approach is to rely on Cerenkov emission emitted from many therapeutic radiopharmaceuticals. This project aims to develop this optical imaging technique to allow quantitative dosimetric studies within pre-clinical imaging experiments. Furthermore the project aims to combine other optical imaging modalities such as fluorescence imaging in order to reveal the physiological and biological response following treatment.
Homepage
Go to homepage
Duration
36 months between Aug 1 2014 and Dec 31 2017
Contact person
Johan Axelsson (johan.axelsson@fysik.lth.se)
Additional information
The Biophotonics Group at the Division of Atomic Physics (Lund University) is pursuing a diversified research programme related to biomedical optics. The work is based on a long experience of laser spectroscopy. Research on the medical applications of laser-induced fluorescence for diagnostic purposes was initiated as early as 1982. The group has since been growing and is presently working within several medical and pharmaceutical applications. This includes research on for example photodynamic therapy of prostate cancer, in vivo monitoring of human tissue, as well as industrial applications such as spectroscopy of pharmaceutical materials. A common factor is the spectroscopic and optical analysis of complex, highly scattering materials such as biological tissue and porous pharmaceutical solids.