Detailed information about selected course/program
EU code
12.1 - Medicine
Mobility
3 - PhD
Location
Free University of Berlin, Germany
Subject
Medical School - Charité - University Medicine Berlin
Course/Program
PhD Degree in Modulation of pain and inflammation in chronic arthritis by opioids
Language
German and English
Language requirements
Participants should be fluent in both written and spoken English. Applicants from countries where English is not the language of instruction need to have obtained a score of at least 550 on the TOEFL test (or a score of at least 213 on a computer TOEFL test) or provide proof of an equivalent test or provide proof that part of their education was in English. Or equal knowledge of German.
Academic requirements
MD or B.Sc.
Max available positions
1
Information
This study aims at modulating pain and inflammation by stimulating the production and secretion, or by inhibiting the extracellular enzymatic degradation of endogenous opioids derived from immune cells. In animal models of inflammation and in patients with inflamed joints we will examine pain, inflammatory parameters, release and extracellular concentrations of opioid peptides, modulated by cytokines, chemokines and peptidase inhibitors. In patients we also compare effects of exogenous (intraarticular morphine) and endogenous opioids (intraarticular peptidase inhibitors). Methods: In vivo pain testing in rats and humans, cloning, mutagenesis, RNA quantification, sequencing, radioimmunoassy, ELISA.
Homepage
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Duration
36 months between Jul 15 2014 and Jul 14 2017
Contact person
C. Stein (christoph.stein@charite.de)
Additional information
personal interview required (through telephone or skype)