Detailed information about selected course/program
EU code
13.1 - Biology
Mobility
3 - PhD
Location
Free University of Berlin, Germany
Subject
Department of Biology, Chemistry, and Pharmacy
Course/Program
PhD Degree in Dissecting roles of miRNAs in subcellular localization and translation of mRNAs
Language
English
Language requirements
Participants should be fluent in both written and spoken English. Applicants from countries where English is not the language of instruction need to have obtained a score of at least 550 on the TOEFL test (or a score of at least 213 on a computer TOEFL test) or provide proof of an equivalent test or provide proof that part of their education was in English.
Academic requirements
MSc degree in Biological Sciences, average grade 2.4 or better (German grading system)
Max available positions
1
Information
Up to 90% of human DNA is estimated to be transcribed into so called non-coding RNAs that are not translated into proteins. Many of them act as potent modifiers of gene expression. miRNAs are a class of such short non-coding RNAs, that regulate translation and stability of mRNAs. In highly polarized cells, many mRNAs have specific subcellular localization patterns and their translation is often regulated in a localization-dependent manner. Many human pathologies, including neurological disorders such as the Fragile X syndrome, are associated with a failure to localize and translate mRNAs at specific subcellular sites. The aim of the project will be to dissect the roles of miRNAs in these processes. The project will involve a combination of biochemical, computational and imaging approaches.
Homepage
Go to homepage
Duration
36 months between Jul 15 2014 and Jul 14 2017
Contact person
Dr. Marina Chekulaeva (Marina.Chekulaeva@mdc-berlin.de)